Profile change history
A deterministic history of records added to PeptideScanner and preserved profile or record revisions connected through the reviewed Afamelanotide identity.
Before and after
We rewrote the profile summary to describe the cited public record more directly. The cited sources and status did not change.
Collection chronology
Showing the latest 55 additions by PeptideScanner publication date; the complete connected record set remains available in Latest Research. Most recent addition: August 22, 2026.
DailyMed lists Structured Product Labeling version 1 for the reviewed Afamelanotide label family with a published date of 2019-12-31. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 10 for the reviewed Afamelanotide label family with a published date of 2026-02-06. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 11 for the reviewed Afamelanotide label family with a published date of 2026-05-13. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 2 for the reviewed Afamelanotide label family with a published date of 2020-03-27. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 3 for the reviewed Afamelanotide label family with a published date of 2020-04-15. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 4 for the reviewed Afamelanotide label family with a published date of 2021-10-04. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 5 for the reviewed Afamelanotide label family with a published date of 2023-01-24. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 6 for the reviewed Afamelanotide label family with a published date of 2023-05-17. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 7 for the reviewed Afamelanotide label family with a published date of 2023-10-17. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 8 for the reviewed Afamelanotide label family with a published date of 2024-08-16. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
DailyMed lists Structured Product Labeling version 9 for the reviewed Afamelanotide label family with a published date of 2025-11-17. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.
The Federal Register published notice 2021-24074, attributed to FDA and its parent HHS department, on 2021-11-04. Its official title is “Determination of Regulatory Review Period for Purposes of Patent Extension; SCENESSE,” and PeptideScanner's exact reviewed identity mapping connects the document to Afamelanotide.
The Federal Register published notice 2023-03364, attributed to FDA and its parent HHS department, on 2023-02-17. Its official title is “Product-Specific Guidances; Draft and Revised Draft Guidances for Industry; Availability,” and PeptideScanner's exact reviewed identity mapping connects the document to Afamelanotide, Glucagon, Leuprolide and Vosoritide.
PeptideScanner retained ClinicalTrials.gov record NCT03634137 at 2026-07-30T21:10:03.005Z. Its registry update date was 2018-08-16, and PeptideScanner's reviewed identity mapping was afamelanotide.
The official Drugs@FDA dataset lists original submission 1 for NDA 210797 with status AP dated 2019-10-08, and names afamelanotide among the application record's active ingredients.
PeptideScanner retained ClinicalTrials.gov record NCT06388642 at 2026-08-10T18:10:03.859Z. Its registry update date was 2026-07-27, and PeptideScanner's reviewed identity mapping was afamelanotide.
PubMed lists PMID 28003770 in The application of clinical genetics as Review, Journal Article, with publication-date metadata of 2016-12-12 (day precision). PeptideScanner associated the retained record with the identity slug afamelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.
PubMed lists PMID 31987791 in Journal of the American Academy of Dermatology as Letter, Randomized Controlled Trial, with publication-date metadata of 2020-01-25 (day precision). PeptideScanner associated the retained record with the identity slug afamelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.
PubMed lists PMID 38784937 in Postepy dermatologii i alergologii as Journal Article, Review, with publication-date metadata of 2024-04-12 (day precision). PeptideScanner associated the retained record with the identity slug afamelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.
PubMed lists PMID 40692281 in Clinical and experimental dermatology as Journal Article, with publication-date metadata of 2025-10-27 (day precision). PeptideScanner associated the retained record with the identity slug afamelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.
PubMed lists PMID 41542313 in JAAD case reports as Case Reports, Journal Article, with publication-date metadata of 2025-11-24 (day precision). PeptideScanner associated the retained record with the identity slug afamelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.
PeptideScanner retained PubMed bibliographic metadata for PMID 25402764 at 2026-07-30T21:22:57.992Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2014-11-18. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 25494545 at 2026-07-30T16:30:52.686Z. PubMed recorded a metadata revision date of 2026-01-28 and an Entrez history date of 2014-12-16. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 25607635 at 2026-07-30T21:09:14.737Z. PubMed recorded a metadata revision date of 2018-12-02 and an Entrez history date of 2015-01-22. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 25607828 at 2026-07-30T21:09:14.737Z. PubMed recorded a metadata revision date of 2018-12-02 and an Entrez history date of 2015-01-22. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 26132941 at 2026-07-30T21:09:16.183Z. PubMed recorded a metadata revision date of 2018-11-13 and an Entrez history date of 2015-07-02. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 26979527 at 2026-07-30T21:22:57.999Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2016-03-17. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 28063031 at 2026-07-30T20:31:47.806Z. PubMed recorded a metadata revision date of 2020-03-06 and an Entrez history date of 2017-01-08. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 30517779 at 2026-07-30T20:44:20.583Z. PubMed recorded a metadata revision date of 2019-11-20 and an Entrez history date of 2018-12-06. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 32459219 at 2026-07-30T20:28:46.334Z. PubMed recorded a metadata revision date of 2020-05-29 and an Entrez history date of 2020-05-28. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 38634774 at 2026-07-30T16:23:36.263Z. PubMed recorded a metadata revision date of 2026-03-06 and an Entrez history date of 2024-04-18. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 38736212 at 2026-07-30T16:23:36.274Z. PubMed recorded a metadata revision date of 2026-03-06 and an Entrez history date of 2024-05-13. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 41793078 at 2026-07-30T16:23:41.287Z. PubMed recorded a metadata revision date of 2026-03-07 and an Entrez history date of 2026-03-07. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 23407924 at 2026-07-30T21:22:57.984Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2013-02-15. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 23884489 at 2026-07-30T21:22:57.985Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2013-07-26. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 25230094 at 2026-07-30T21:22:57.990Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2014-09-18. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 25470471 at 2026-07-30T21:22:57.992Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2014-12-04. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 21073357 at 2026-07-30T21:22:57.974Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2010-11-16. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 21597671 at 2026-07-30T21:22:57.976Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2011-05-21. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 23277150 at 2026-07-30T21:22:57.983Z. PubMed recorded a metadata revision date of 2017-11-16 and an Entrez history date of 2013-01-02. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 41547183 at 2026-07-30T16:14:14.777Z. PubMed recorded a metadata revision date of 2026-06-26 and an Entrez history date of 2026-01-17. PeptideScanner associated this retained record with the identity slug afamelanotide. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained ClinicalTrials.gov record NCT00859534 at 2026-07-30T22:26:45.018Z. Its registry update date was 2009-09-15, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT00979745 at 2026-07-30T19:57:27.405Z. Its registry update date was 2021-10-12, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT01097044 at 2026-07-30T20:44:36.694Z. Its registry update date was 2019-10-28, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT01382589 at 2026-07-30T21:55:56.622Z. Its registry update date was 2013-03-22, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT01430195 at 2026-07-30T21:55:56.618Z. Its registry update date was 2013-03-22, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT01605136 at 2026-07-30T20:45:58.280Z. Its registry update date was 2019-09-19, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT04053270 at 2026-07-30T20:44:36.678Z. Its registry update date was 2019-10-10, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT04425746 at 2026-07-30T19:57:27.405Z. Its registry update date was 2021-10-01, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT04578496 at 2026-07-30T20:20:00.372Z. Its registry update date was 2020-11-19, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT04704713 at 2026-07-30T20:05:17.854Z. Its registry update date was 2021-03-19, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT04943159 at 2026-07-30T19:57:27.404Z. Its registry update date was 2021-10-26, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT05368857 at 2026-07-30T19:16:22.169Z. Its registry update date was 2023-02-09, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT04525157 at 2026-07-30T19:08:50.172Z. Its registry update date was 2023-09-22, and PeptideScanner's reviewed identity mapping was afamelanotide.
PeptideScanner retained ClinicalTrials.gov record NCT04962503 at 2026-07-30T19:14:02.188Z. Its registry update date was 2023-04-11, and PeptideScanner's reviewed identity mapping was afamelanotide.