Profile change history

What changed for Ipamorelin?

A deterministic history of records added to PeptideScanner and preserved profile or record revisions connected through the reviewed Ipamorelin identity.

18Total events
17Record additions
1Version changes
7Cited source years

Before and after

Preserved version changes

Correction

Ipamorelin profile

We added FDA's dated assessment to distinguish substance forms, evaluated uses and the advisory stage of review. Earlier profile versions remain available.

PeptideScanner change date
September 15, 2026
Evidence lane
Profile

Profile summary

Before
A peptide named in FDA compounding-risk and DOJ enforcement records.
After
FDA's August 2024 assessment distinguishes ipamorelin free base and acetate and evaluates evidence for growth hormone deficiency and postoperative ileus.

Evidence note

Before
FDA's compounding-risk page describes immunogenicity and characterization concerns. A separate Justice Department release names Ipamorelin among unapproved new drugs distributed by the cited pharmacy.
After
At the time of its assessment, FDA reported that neither form was a component of an FDA-approved drug and found insufficient evidence for the evaluated uses. The advisory briefing is not a final compounding determination.

Cited source records

Before
fda-bulk-peptide-risks, doj-unapproved-peptide-enforcement
After
fda-bulk-peptide-risks, doj-unapproved-peptide-enforcement, fda-ipamorelin-briefing-2024

Claim citations

Before
name: doj-unapproved-peptide-enforcement; aliases: fda-bulk-peptide-risks; category: fda-bulk-peptide-risks, doj-unapproved-peptide-enforcement; status: doj-unapproved-peptide-enforcement; summary: fda-bulk-peptide-risks, doj-unapproved-peptide-enforcement; evidenceNote: fda-bulk-peptide-risks, doj-unapproved-peptide-enforcement
After
name: doj-unapproved-peptide-enforcement; aliases: fda-bulk-peptide-risks; category: fda-bulk-peptide-risks, doj-unapproved-peptide-enforcement; status: doj-unapproved-peptide-enforcement; summary: fda-ipamorelin-briefing-2024; evidenceNote: fda-ipamorelin-briefing-2024

Collection chronology

Evidence added to PeptideScanner

Browse all 17 connected records →

Showing the latest 17 additions by PeptideScanner publication date; the complete connected record set remains available in Latest Research. Most recent addition: August 21, 2026.

Record added

Federal Register notice 2024-21241

The Federal Register published notice 2024-21241, attributed to FDA and its parent HHS department, on 2024-09-18. Its official title is “Pharmacy Compounding Advisory Committee; Notice of Meeting; Establishment of a Public Docket; Request for Comments-Bulk Drug Substances Nominated for Inclusion on the Section 503A Bulk Drug Substances List; Revisions to the Withdrawn or Removed List,” and PeptideScanner's exact reviewed identity mapping connects the document to Ipamorelin.

PeptideScanner change date
August 21, 2026
Cited source date
September 18, 2024
Evidence lane
Regulatory
Record added

The influence of ghrelin agonist ipamorelin acetate on the hypothalamic-pituitary-testicular axis in a cichlid fish, Oreochromis mossambicus.

PubMed lists PMID 38996787 in Animal reproduction science as Journal Article, with publication-date metadata of 2024-07-05 (day precision). PeptideScanner associated the retained record with the identity slug ipamorelin. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
August 27, 2024
Evidence lane
Literature metadata
Record added

PubMed record PMID 10496658

PeptideScanner retained PubMed bibliographic metadata for PMID 10496658 at 2026-07-30T20:48:24.176Z. PubMed recorded a metadata revision date of 2019-08-18 and an Entrez history date of 1999-09-25. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
August 18, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 11459660

PeptideScanner retained PubMed bibliographic metadata for PMID 11459660 at 2026-07-30T20:48:24.201Z. PubMed recorded a metadata revision date of 2019-08-19 and an Entrez history date of 2001-07-19. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
August 19, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 25869809

PeptideScanner retained PubMed bibliographic metadata for PMID 25869809 at 2026-07-30T20:43:08.964Z. PubMed recorded a metadata revision date of 2019-12-10 and an Entrez history date of 2015-04-15. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
December 10, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 9849822

PeptideScanner retained PubMed bibliographic metadata for PMID 9849822 at 2026-07-30T20:46:59.652Z. PubMed recorded a metadata revision date of 2019-09-05 and an Entrez history date of 1998-12-16. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
September 5, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 9879640

PeptideScanner retained PubMed bibliographic metadata for PMID 9879640 at 2026-07-30T20:46:59.653Z. PubMed recorded a metadata revision date of 2019-09-09 and an Entrez history date of 1999-01-08. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
September 9, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 10828840

PeptideScanner retained PubMed bibliographic metadata for PMID 10828840 at 2026-07-30T20:50:07.370Z. PubMed recorded a metadata revision date of 2019-07-09 and an Entrez history date of 2000-06-01. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
July 9, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 15665799

PeptideScanner retained PubMed bibliographic metadata for PMID 15665799 at 2026-07-30T21:09:05.701Z. PubMed recorded a metadata revision date of 2018-12-17 and an Entrez history date of 2005-01-25. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
December 17, 2018
Evidence lane
Literature metadata
Record added

PubMed record PMID 25331030

PeptideScanner retained PubMed bibliographic metadata for PMID 25331030 at 2026-07-30T16:20:34.456Z. PubMed recorded a metadata revision date of 2026-05-18 and an Entrez history date of 2014-10-22. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
May 18, 2026
Evidence lane
Literature metadata
Record added

PubMed record PMID 39043357

PeptideScanner retained PubMed bibliographic metadata for PMID 39043357 at 2026-07-30T16:20:38.933Z. PubMed recorded a metadata revision date of 2026-05-24 and an Entrez history date of 2024-07-23. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
May 24, 2026
Evidence lane
Literature metadata
Record added

PubMed record PMID 10373343

PeptideScanner retained PubMed bibliographic metadata for PMID 10373343 at 2026-07-30T22:15:26.481Z. PubMed recorded a metadata revision date of 2012-11-15 and an Entrez history date of 1999-06-22. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 15, 2012
Evidence lane
Literature metadata
Record added

PubMed record PMID 11735244

PeptideScanner retained PubMed bibliographic metadata for PMID 11735244 at 2026-07-30T21:56:55.059Z. PubMed recorded a metadata revision date of 2013-11-21 and an Entrez history date of 2001-12-12. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 21, 2013
Evidence lane
Literature metadata
Record added

PubMed record PMID 12168778

PeptideScanner retained PubMed bibliographic metadata for PMID 12168778 at 2026-07-30T21:25:18.666Z. PubMed recorded a metadata revision date of 2017-05-29 and an Entrez history date of 2002-08-10. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
May 29, 2017
Evidence lane
Literature metadata
Record added

PubMed record PMID 9733495

PeptideScanner retained PubMed bibliographic metadata for PMID 9733495 at 2026-07-30T21:08:59.367Z. PubMed recorded a metadata revision date of 2018-12-01 and an Entrez history date of 1998-09-11. PeptideScanner associated this retained record with the identity slug ipamorelin. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
December 1, 2018
Evidence lane
Literature metadata
Record added

ClinicalTrials.gov record NCT01280344

PeptideScanner retained ClinicalTrials.gov record NCT01280344 at 2026-07-30T21:24:24.229Z. Its registry update date was 2017-04-13, and PeptideScanner's reviewed identity mapping was ipamorelin.

PeptideScanner change date
August 9, 2026
Cited source date
April 13, 2017
Evidence lane
Clinical trials
Record added

ClinicalTrials.gov record NCT00672074

PeptideScanner retained ClinicalTrials.gov record NCT00672074 at 2026-07-30T21:24:24.228Z. Its registry update date was 2017-04-14, and PeptideScanner's reviewed identity mapping was ipamorelin.

PeptideScanner change date
August 8, 2026
Cited source date
April 14, 2017
Evidence lane
Clinical trials