We clarified that CJC-1295 with DAC is a related, distinct active moiety rather than an interchangeable form. The FDA briefing describes five bulk substances; clinical findings must retain the studied form.
PeptideScanner change date
September 15, 2026
Evidence lane
Profile
Profile summary
Before
A peptide named in FDA compounding-risk and DOJ enforcement records.
After
FDA evaluates CJC-1295 and CJC-1295 with drug affinity complex (DAC) as distinct active moieties, with several salt forms.
Evidence note
Before
FDA's compounding-risk page describes immunogenicity, impurity, and adverse-event concerns. A separate Justice Department release names CJC 1295 among unapproved new drugs distributed by the cited pharmacy.
After
FDA's 2024 briefing distinguishes five bulk substances and reports that none is a component of an FDA-approved drug. Evidence for a DAC-modified substance cannot automatically establish effects for a non-DAC form.
Showing the latest 9 additions by PeptideScanner publication date; the complete connected record set remains available in Latest Research. Most recent addition: August 21, 2026.
The Federal Register published notice 2024-24828, attributed to FDA and its parent HHS department, on 2024-10-25. Its official title is “Pharmacy Compounding Advisory Committee; Notice of Meeting; Establishment of a Public Docket; Request for Comments-Bulk Drug Substances Nominated for Inclusion on the Section 503A Bulk Drug Substances List,” and PeptideScanner's exact reviewed identity mapping connects the document to CJC-1295.
PeptideScanner retained PubMed bibliographic metadata for PMID 17018654 at 2026-07-30T21:09:06.872Z. PubMed recorded a metadata revision date of 2018-12-01 and an Entrez history date of 2006-10-05. PeptideScanner associated this retained record with the identity slug cjc-1295. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 19386527 at 2026-07-30T18:28:26.873Z. PubMed recorded a metadata revision date of 2025-05-29 and an Entrez history date of 2009-04-24. PeptideScanner associated this retained record with the identity slug cjc-1295. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 30489688 at 2026-07-30T20:43:12.045Z. PubMed recorded a metadata revision date of 2019-12-10 and an Entrez history date of 2018-11-30. PeptideScanner associated this retained record with the identity slug cjc-1295. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 30938069 at 2026-07-30T20:34:12.987Z. PubMed recorded a metadata revision date of 2020-01-13 and an Entrez history date of 2019-04-03. PeptideScanner associated this retained record with the identity slug cjc-1295. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 15817669 at 2026-07-30T22:26:16.765Z. PubMed recorded a metadata revision date of 2010-11-18 and an Entrez history date of 2005-04-09. PeptideScanner associated this retained record with the identity slug cjc-1295. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 16352683 at 2026-07-30T21:09:05.761Z. PubMed recorded a metadata revision date of 2018-12-01 and an Entrez history date of 2005-12-15. PeptideScanner associated this retained record with the identity slug cjc-1295. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 21204297 at 2026-07-30T21:38:23.138Z. PubMed recorded a metadata revision date of 2016-05-11 and an Entrez history date of 2011-01-05. PeptideScanner associated this retained record with the identity slug cjc-1295. These dates describe PubMed metadata history, not the article's original publication date.
PeptideScanner retained PubMed bibliographic metadata for PMID 26771670 at 2026-07-30T21:35:57.020Z. PubMed recorded a metadata revision date of 2016-12-30 and an Entrez history date of 2016-01-16. PeptideScanner associated this retained record with the identity slug cjc-1295. These dates describe PubMed metadata history, not the article's original publication date.