Profile change history

What changed for Bremelanotide?

A deterministic history of records added to PeptideScanner and preserved profile or record revisions connected through the reviewed Bremelanotide identity.

31Total events
29Record additions
2Version changes
13Cited source years

Before and after

Preserved version changes

Profile updated

Bremelanotide profile

We added search aliases that the cited FDA substance-identity record maps to this active ingredient. The profile's status did not change.

PeptideScanner change date
July 29, 2026
Evidence lane
Profile

Related names

Before
Vyleesi
After
Vyleesi, PT-141

Cited source records

Before
dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1
After
dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1, fda-bremelanotide-identity

Claim citations

Before
name: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; aliases: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; category: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; status: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; summary: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; evidenceNote: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1
After
name: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; aliases: fda-bremelanotide-identity; category: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; status: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; summary: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1; evidenceNote: dailymed-bremelanotide-f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf-v1
Profile updated

Bremelanotide profile

We rewrote the profile summary to describe the cited public record more directly. The cited sources and status did not change.

PeptideScanner change date
July 27, 2026
Evidence lane
Profile

Profile summary

Before
A melanocortin receptor agonist peptide represented by one exact U.S. label record.
After
A melanocortin receptor agonist peptide. This profile cites a U.S. label record.

Collection chronology

Evidence added to PeptideScanner

Browse all 29 connected records →

Showing the latest 29 additions by PeptideScanner publication date; the complete connected record set remains available in Latest Research. Most recent addition: August 22, 2026.

Record added

Bremelanotide DailyMed SPL version 1

DailyMed lists Structured Product Labeling version 1 for the reviewed Bremelanotide label family with a published date of 2025-11-18. PeptideScanner retained the exact versioned ZIP byte count and SHA-256 receipt without republishing its contents.

PeptideScanner change date
August 22, 2026
Cited source date
November 18, 2025
Evidence lane
Regulatory
Record added

Federal Register notice 2020-18240

The Federal Register published notice 2020-18240, attributed to FDA and its parent HHS department, on 2020-08-20. Its official title is “Determination of Regulatory Review Period for Purposes of Patent Extension; VYLEESI,” and PeptideScanner's exact reviewed identity mapping connects the document to Bremelanotide.

PeptideScanner change date
August 21, 2026
Cited source date
August 20, 2020
Evidence lane
Regulatory
Record added

Federal Register notice 2021-06202

The Federal Register published notice 2021-06202, attributed to FDA and its parent HHS department, on 2021-03-25. Its official title is “Product-Specific Guidances; Draft and Revised Draft Guidances for Industry; Availability,” and PeptideScanner's exact reviewed identity mapping connects the document to Bremelanotide and Octreotide.

PeptideScanner change date
August 21, 2026
Cited source date
March 25, 2021
Evidence lane
Regulatory
Record added

ClinicalTrials.gov record NCT04943068

PeptideScanner retained ClinicalTrials.gov record NCT04943068 at 2026-07-30T18:38:25.522Z. Its registry update date was 2024-11-13, and PeptideScanner's reviewed identity mapping was bremelanotide.

PeptideScanner change date
August 14, 2026
Cited source date
November 13, 2024
Evidence lane
Clinical trials
Record added

Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics.

PubMed lists PMID 32353679 in Journal of pharmaceutical and biomedical analysis as Journal Article, with publication-date metadata of 2020-03-27 (day precision). PeptideScanner associated the retained record with the identity slug bremelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
August 1, 2024
Evidence lane
Literature metadata
Record added

The neurobiology of bremelanotide for the treatment of hypoactive sexual desire disorder in premenopausal women.

PubMed lists PMID 33455598 in CNS spectrums as Journal Article, Review, Research Support, Non-U.S. Gov't, with publication-date metadata of 2021-01-18 (day precision). PeptideScanner associated the retained record with the identity slug bremelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
June 27, 2022
Evidence lane
Literature metadata
Record added

Bremelanotide for Treatment of Female Hypoactive Sexual Desire.

PubMed lists PMID 35076581 in Neurology international as Journal Article, Review, with publication-date metadata of 2022-01-04 (day precision). PeptideScanner associated the retained record with the identity slug bremelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
January 28, 2022
Evidence lane
Literature metadata
Record added

Prespecified and Integrated Subgroup Analyses from the RECONNECT Phase 3 Studies of Bremelanotide.

PubMed lists PMID 35230162 in Journal of women's health (2002) as Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, with publication-date metadata of 2022-02-25 (day precision). PeptideScanner associated the retained record with the identity slug bremelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
March 15, 2022
Evidence lane
Literature metadata
Record added

An evaluation of bremelanotide injection for the treatment of hypoactive sexual desire disorder.

PubMed lists PMID 36242769 in Expert opinion on pharmacotherapy as Journal Article, Review, with publication-date metadata of 2022-10-18 (day precision). PeptideScanner associated the retained record with the identity slug bremelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
January 17, 2023
Evidence lane
Literature metadata
Record added

PubMed record PMID 12851303

PeptideScanner retained PubMed bibliographic metadata for PMID 12851303 at 2026-07-30T20:51:53.921Z. PubMed recorded a metadata revision date of 2019-06-16 and an Entrez history date of 2003-07-10. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
June 16, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 27977473

PeptideScanner retained PubMed bibliographic metadata for PMID 27977473 at 2026-07-30T21:09:23.592Z. PubMed recorded a metadata revision date of 2018-12-02 and an Entrez history date of 2016-12-16. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
December 2, 2018
Evidence lane
Literature metadata
Record added

PubMed record PMID 28189361

PeptideScanner retained PubMed bibliographic metadata for PMID 28189361 at 2026-07-30T20:55:52.311Z. PubMed recorded a metadata revision date of 2019-03-18 and an Entrez history date of 2017-02-13. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
March 18, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 30290453

PeptideScanner retained PubMed bibliographic metadata for PMID 30290453 at 2026-07-30T20:44:20.566Z. PubMed recorded a metadata revision date of 2019-11-20 and an Entrez history date of 2018-10-07. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 20, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 31277966

PeptideScanner retained PubMed bibliographic metadata for PMID 31277966 at 2026-07-30T20:27:29.445Z. PubMed recorded a metadata revision date of 2020-06-29 and an Entrez history date of 2019-07-07. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
June 29, 2020
Evidence lane
Literature metadata
Record added

PubMed record PMID 31381550

PeptideScanner retained PubMed bibliographic metadata for PMID 31381550 at 2026-07-30T20:44:20.977Z. PubMed recorded a metadata revision date of 2019-11-08 and an Entrez history date of 2019-08-06. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 8, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 31429064

PeptideScanner retained PubMed bibliographic metadata for PMID 31429064 at 2026-07-30T20:33:07.992Z. PubMed recorded a metadata revision date of 2020-02-25 and an Entrez history date of 2019-08-21. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
February 25, 2020
Evidence lane
Literature metadata
Record added

PubMed record PMID 41960633

PeptideScanner retained PubMed bibliographic metadata for PMID 41960633 at 2026-07-30T16:22:18.490Z. PubMed recorded a metadata revision date of 2026-04-24 and an Entrez history date of 2026-04-10. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
April 24, 2026
Evidence lane
Literature metadata
Record added

PubMed record PMID 16839319

PeptideScanner retained PubMed bibliographic metadata for PMID 16839319 at 2026-07-30T21:22:56.974Z. PubMed recorded a metadata revision date of 2017-10-16 and an Entrez history date of 2006-07-15. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
October 16, 2017
Evidence lane
Literature metadata
Record added

PubMed record PMID 27751477

PeptideScanner retained PubMed bibliographic metadata for PMID 27751477 at 2026-07-30T21:09:23.546Z. PubMed recorded a metadata revision date of 2018-12-02 and an Entrez history date of 2016-10-19. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
December 2, 2018
Evidence lane
Literature metadata
Record added

PubMed record PMID 39793696

PeptideScanner retained PubMed bibliographic metadata for PMID 39793696 at 2026-07-30T16:20:39.143Z. PubMed recorded a metadata revision date of 2026-05-24 and an Entrez history date of 2025-01-10. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
May 24, 2026
Evidence lane
Literature metadata
Record added

PubMed record PMID 42485063

PeptideScanner retained PubMed bibliographic metadata for PMID 42485063 at 2026-08-10T18:13:56.710Z. PubMed recorded a metadata revision date of 2026-07-22 and an Entrez history date of 2026-07-22. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
July 22, 2026
Evidence lane
Literature metadata
Record added

PubMed record PMID 14963471

PeptideScanner retained PubMed bibliographic metadata for PMID 14963471 at 2026-07-30T21:55:37.950Z. PubMed recorded a metadata revision date of 2014-11-20 and an Entrez history date of 2004-02-14. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 20, 2014
Evidence lane
Literature metadata
Record added

PubMed record PMID 14999221

PeptideScanner retained PubMed bibliographic metadata for PMID 14999221 at 2026-07-30T21:41:07.288Z. PubMed recorded a metadata revision date of 2015-11-19 and an Entrez history date of 2004-03-05. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 19, 2015
Evidence lane
Literature metadata
Record added

PubMed record PMID 15134289

PeptideScanner retained PubMed bibliographic metadata for PMID 15134289 at 2026-07-30T21:55:37.950Z. PubMed recorded a metadata revision date of 2014-11-20 and an Entrez history date of 2004-05-12. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 20, 2014
Evidence lane
Literature metadata
Record added

PubMed record PMID 15833522

PeptideScanner retained PubMed bibliographic metadata for PMID 15833522 at 2026-07-30T21:41:07.293Z. PubMed recorded a metadata revision date of 2015-11-19 and an Entrez history date of 2005-04-19. PeptideScanner associated this retained record with the identity slug bremelanotide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 19, 2015
Evidence lane
Literature metadata
Record added

ClinicalTrials.gov record NCT00425256

PeptideScanner retained ClinicalTrials.gov record NCT00425256 at 2026-07-30T22:15:58.882Z. Its registry update date was 2011-02-23, and PeptideScanner's reviewed identity mapping was bremelanotide.

PeptideScanner change date
August 9, 2026
Cited source date
February 23, 2011
Evidence lane
Clinical trials
Record added

ClinicalTrials.gov record NCT01382719

PeptideScanner retained ClinicalTrials.gov record NCT01382719 at 2026-07-30T21:54:46.551Z. Its registry update date was 2014-12-18, and PeptideScanner's reviewed identity mapping was bremelanotide.

PeptideScanner change date
August 9, 2026
Cited source date
December 18, 2014
Evidence lane
Clinical trials
Record added

ClinicalTrials.gov record NCT05709444

PeptideScanner retained ClinicalTrials.gov record NCT05709444 at 2026-07-30T18:39:33.780Z. Its registry update date was 2024-10-17, and PeptideScanner's reviewed identity mapping was bremelanotide.

PeptideScanner change date
August 8, 2026
Cited source date
October 17, 2024
Evidence lane
Clinical trials