# Development and Validation of a Stability-Indicating RS HPLC Method for Leuprolide Acetate and Its Related Substances: Characterization of Degradation Products With LC-MS.

> PubMed lists PMID 42299119 in Biomedical chromatography : BMC as Journal Article, with publication-date metadata of 2026-07 (month precision). PeptideScanner associated the retained record with the identity slug leuprolide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

- Evidence object: `story:pubmed-pmid-42299119-leuprolide:v1`
- Evidence domain: Literature metadata
- Date in source: 2026-06-16
- Source checked: 2026-07-30
- Published by PeptideScanner: 2026-08-13
- Story landing page: https://peptidescanner.com/stories/pubmed-pmid-42299119-leuprolide/
- JSON record: https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-42299119-leuprolide-v1.json
- Content SHA-256: `647683b013e400f6b0462065e35418b8a3da8a2a538df9ff026d1fa6334cafe3`

## Claims and source pins

### Headline

Development and Validation of a Stability-Indicating RS HPLC Method for Leuprolide Acetate and Its Related Substances: Characterization of Degradation Products With LC-MS. ([`pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306`](#source-pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306))

### Summary

PubMed lists PMID 42299119 in Biomedical chromatography : BMC as Journal Article, with publication-date metadata of 2026-07 (month precision). PeptideScanner associated the retained record with the identity slug leuprolide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306`](#source-pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306))

### Paragraph 1

PubMed lists PMID 42299119 in Biomedical chromatography : BMC as Journal Article, with publication-date metadata of 2026-07 (month precision). PeptideScanner associated the retained record with the identity slug leuprolide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306`](#source-pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306))

### Paragraph 2

This page reproduces bounded bibliographic metadata attributed to PubMed. Its title and publication details are source metadata, not PeptideScanner's endorsement or an assertion of safety, efficacy, or scientific truth. ([`pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306`](#source-pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306))

## Sources

<a id="source-pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306"></a>
- **Development and Validation of a Stability-Indicating RS HPLC Method for Leuprolide Acetate and Its Related Substances: Characterization of Degradation Products With LC-MS. · retained source version 1:2026-06-16:current:a72a3b0b23069215b1d687e2b1a48169ccd0b5b3821f5a89b1f18a666be6c3b3** — PubMed; class A. [Open source](https://pubmed.ncbi.nlm.nih.gov/42299119/) (`pubmed-observation-pmid-42299119-2026-06-16-a72a3b0b2306`)

## Correction lineage

No correction is recorded for this version.

## Reporting boundaries and unknowns

PeptideScanner reproduces bounded bibliographic metadata attributed to PubMed. It does not summarize or endorse the article's findings.

- Sources outside the selected public PeptideScanner bundle may exist and are not represented by this object.
- This object does not determine whether cited records agree, corroborate one another, or establish scientific truth.
- This object does not determine safety, efficacy, causality, or suitability for any person.

Methodology: https://peptidescanner.com/methodology/
Medical disclaimer: https://peptidescanner.com/medical-disclaimer/

## Suggested citation

PeptideScanner. "Development and Validation of a Stability-Indicating RS HPLC Method for Leuprolide Acetate and Its Related Substances: Characterization of Degradation Products With LC-MS." Version 1, published 2026-08-13. https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-42299119-leuprolide-v1.json SHA-256: 647683b013e400f6b0462065e35418b8a3da8a2a538df9ff026d1fa6334cafe3.

