# Thermally Stressed Solid-State Stability of Semaglutide: Understanding the Influence of Temperature on Protein Content, Secondary Structure, Phase Transition, and Chemical Degradation.

> PubMed lists PMID 42086873 in Pharmaceutical research as Journal Article, with publication-date metadata of 2026-05-05 (day precision). PeptideScanner associated the retained record with the identity slug semaglutide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

- Evidence object: `story:pubmed-pmid-42086873-semaglutide:v1`
- Evidence domain: Literature metadata
- Date in source: 2026-06-29
- Source checked: 2026-07-30
- Published by PeptideScanner: 2026-08-14
- Story landing page: https://peptidescanner.com/stories/pubmed-pmid-42086873-semaglutide/
- JSON record: https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-42086873-semaglutide-v1.json
- Content SHA-256: `c6ef628a95d9d4ddf8299c9ff96d5256472e3d08612622614789b6d7bf43df59`

## Claims and source pins

### Headline

Thermally Stressed Solid-State Stability of Semaglutide: Understanding the Influence of Temperature on Protein Content, Secondary Structure, Phase Transition, and Chemical Degradation. ([`pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba`](#source-pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba))

### Summary

PubMed lists PMID 42086873 in Pharmaceutical research as Journal Article, with publication-date metadata of 2026-05-05 (day precision). PeptideScanner associated the retained record with the identity slug semaglutide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba`](#source-pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba))

### Paragraph 1

PubMed lists PMID 42086873 in Pharmaceutical research as Journal Article, with publication-date metadata of 2026-05-05 (day precision). PeptideScanner associated the retained record with the identity slug semaglutide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba`](#source-pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba))

### Paragraph 2

This page reproduces bounded bibliographic metadata attributed to PubMed. Its title and publication details are source metadata, not PeptideScanner's endorsement or an assertion of safety, efficacy, or scientific truth. ([`pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba`](#source-pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba))

## Sources

<a id="source-pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba"></a>
- **Thermally Stressed Solid-State Stability of Semaglutide: Understanding the Influence of Temperature on Protein Content, Secondary Structure, Phase Transition, and Chemical Degradation. · retained source version 1:2026-06-29:current:01df55bc35ba61dcdf88511fdbd5b239443c93fc0c78b7c86aa7f1e3e39caa6f** — PubMed; class A. [Open source](https://pubmed.ncbi.nlm.nih.gov/42086873/) (`pubmed-observation-pmid-42086873-2026-06-29-01df55bc35ba`)

## Correction lineage

No correction is recorded for this version.

## Reporting boundaries and unknowns

PeptideScanner reproduces bounded bibliographic metadata attributed to PubMed. It does not summarize or endorse the article's findings.

- Sources outside the selected public PeptideScanner bundle may exist and are not represented by this object.
- This object does not determine whether cited records agree, corroborate one another, or establish scientific truth.
- This object does not determine safety, efficacy, causality, or suitability for any person.

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## Suggested citation

PeptideScanner. "Thermally Stressed Solid-State Stability of Semaglutide: Understanding the Influence of Temperature on Protein Content, Secondary Structure, Phase Transition, and Chemical Degradation." Version 1, published 2026-08-14. https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-42086873-semaglutide-v1.json SHA-256: c6ef628a95d9d4ddf8299c9ff96d5256472e3d08612622614789b6d7bf43df59.