# Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor.

> PubMed lists PMID 35931197 in Life sciences as Journal Article, with publication-date metadata of 2022-08-02 (day precision). PeptideScanner associated the retained record with the identity slug setmelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

- Evidence object: `story:pubmed-pmid-35931197-setmelanotide:v1`
- Evidence domain: Literature metadata
- Date in source: 2022-10-14
- Source checked: 2026-07-30
- Published by PeptideScanner: 2026-08-13
- Story landing page: https://peptidescanner.com/stories/pubmed-pmid-35931197-setmelanotide/
- JSON record: https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-35931197-setmelanotide-v1.json
- Content SHA-256: `a07cfb4536dfe8a7a75b1279827c5e8cf706a36a84c052ff1a1119c973e92a9f`

## Claims and source pins

### Headline

Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor. ([`pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389`](#source-pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389))

### Summary

PubMed lists PMID 35931197 in Life sciences as Journal Article, with publication-date metadata of 2022-08-02 (day precision). PeptideScanner associated the retained record with the identity slug setmelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389`](#source-pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389))

### Paragraph 1

PubMed lists PMID 35931197 in Life sciences as Journal Article, with publication-date metadata of 2022-08-02 (day precision). PeptideScanner associated the retained record with the identity slug setmelanotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389`](#source-pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389))

### Paragraph 2

This page reproduces bounded bibliographic metadata attributed to PubMed. Its title and publication details are source metadata, not PeptideScanner's endorsement or an assertion of safety, efficacy, or scientific truth. ([`pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389`](#source-pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389))

## Sources

<a id="source-pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389"></a>
- **Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor. · retained source version 1:2022-10-14:current:6fd161d3c3895b07649d0e651156a67a67a8653466609e25db6a65bc9deeb9a7** — PubMed; class A. [Open source](https://pubmed.ncbi.nlm.nih.gov/35931197/) (`pubmed-observation-pmid-35931197-2022-10-14-6fd161d3c389`)

## Correction lineage

No correction is recorded for this version.

## Reporting boundaries and unknowns

PeptideScanner reproduces bounded bibliographic metadata attributed to PubMed. It does not summarize or endorse the article's findings.

- Sources outside the selected public PeptideScanner bundle may exist and are not represented by this object.
- This object does not determine whether cited records agree, corroborate one another, or establish scientific truth.
- This object does not determine safety, efficacy, causality, or suitability for any person.

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## Suggested citation

PeptideScanner. "Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor." Version 1, published 2026-08-13. https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-35931197-setmelanotide-v1.json SHA-256: a07cfb4536dfe8a7a75b1279827c5e8cf706a36a84c052ff1a1119c973e92a9f.