# Health Care Resource Use and Costs Pre- and Post-Treatment Initiation With Linaclotide: Retrospective Analyses of a U.S. Insured Population.

> PubMed lists PMID 29451468 in Managed care (Langhorne, Pa.) as Journal Article, with publication-date metadata of 2018-02 (month precision). PeptideScanner associated the retained record with the identity slug linaclotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

- Evidence object: `story:pubmed-pmid-29451468-linaclotide:v1`
- Evidence domain: Literature metadata
- Date in source: 2026-01-27
- Source checked: 2026-07-30
- Published by PeptideScanner: 2026-08-13
- Story landing page: https://peptidescanner.com/stories/pubmed-pmid-29451468-linaclotide/
- JSON record: https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-29451468-linaclotide-v1.json
- Content SHA-256: `06ecd12ca809c2b78cb08721c722447b7c0ee9ab655285b99849798576368b23`

## Claims and source pins

### Headline

Health Care Resource Use and Costs Pre- and Post-Treatment Initiation With Linaclotide: Retrospective Analyses of a U.S. Insured Population. ([`pubmed-observation-pmid-29451468-2026-01-27-29289767d64c`](#source-pubmed-observation-pmid-29451468-2026-01-27-29289767d64c))

### Summary

PubMed lists PMID 29451468 in Managed care (Langhorne, Pa.) as Journal Article, with publication-date metadata of 2018-02 (month precision). PeptideScanner associated the retained record with the identity slug linaclotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-29451468-2026-01-27-29289767d64c`](#source-pubmed-observation-pmid-29451468-2026-01-27-29289767d64c))

### Paragraph 1

PubMed lists PMID 29451468 in Managed care (Langhorne, Pa.) as Journal Article, with publication-date metadata of 2018-02 (month precision). PeptideScanner associated the retained record with the identity slug linaclotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-29451468-2026-01-27-29289767d64c`](#source-pubmed-observation-pmid-29451468-2026-01-27-29289767d64c))

### Paragraph 2

This page reproduces bounded bibliographic metadata attributed to PubMed. Its title and publication details are source metadata, not PeptideScanner's endorsement or an assertion of safety, efficacy, or scientific truth. ([`pubmed-observation-pmid-29451468-2026-01-27-29289767d64c`](#source-pubmed-observation-pmid-29451468-2026-01-27-29289767d64c))

## Sources

<a id="source-pubmed-observation-pmid-29451468-2026-01-27-29289767d64c"></a>
- **Health Care Resource Use and Costs Pre- and Post-Treatment Initiation With Linaclotide: Retrospective Analyses of a U.S. Insured Population. · retained source version 1:2026-01-27:current:29289767d64c091c0d5be19586103dc4b34608643fb9b8f2e8eb10e0d0e6f82c** — PubMed; class A. [Open source](https://pubmed.ncbi.nlm.nih.gov/29451468/) (`pubmed-observation-pmid-29451468-2026-01-27-29289767d64c`)

## Correction lineage

No correction is recorded for this version.

## Reporting boundaries and unknowns

PeptideScanner reproduces bounded bibliographic metadata attributed to PubMed. It does not summarize or endorse the article's findings.

- Sources outside the selected public PeptideScanner bundle may exist and are not represented by this object.
- This object does not determine whether cited records agree, corroborate one another, or establish scientific truth.
- This object does not determine safety, efficacy, causality, or suitability for any person.

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## Suggested citation

PeptideScanner. "Health Care Resource Use and Costs Pre- and Post-Treatment Initiation With Linaclotide: Retrospective Analyses of a U.S. Insured Population." Version 1, published 2026-08-13. https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-29451468-linaclotide-v1.json SHA-256: 06ecd12ca809c2b78cb08721c722447b7c0ee9ab655285b99849798576368b23.