# A Randomized Phase III Clinical Trial of Plecanatide, a Uroguanylin Analog, in Patients With Chronic Idiopathic Constipation.

> PubMed lists PMID 28169285 in The American journal of gastroenterology as Clinical Trial, Phase III, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, with publication-date metadata of 2017-02-07 (day precision). PeptideScanner associated the retained record with the identity slug plecanatide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

- Evidence object: `story:pubmed-pmid-28169285-plecanatide:v1`
- Evidence domain: Literature metadata
- Date in source: 2022-04-08
- Source checked: 2026-07-30
- Published by PeptideScanner: 2026-08-13
- Story landing page: https://peptidescanner.com/stories/pubmed-pmid-28169285-plecanatide/
- JSON record: https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-28169285-plecanatide-v1.json
- Content SHA-256: `caf39155b44540101049a94958499ece72c21a41e0d3d036f15514005cf26fa7`

## Claims and source pins

### Headline

A Randomized Phase III Clinical Trial of Plecanatide, a Uroguanylin Analog, in Patients With Chronic Idiopathic Constipation. ([`pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0`](#source-pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0))

### Summary

PubMed lists PMID 28169285 in The American journal of gastroenterology as Clinical Trial, Phase III, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, with publication-date metadata of 2017-02-07 (day precision). PeptideScanner associated the retained record with the identity slug plecanatide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0`](#source-pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0))

### Paragraph 1

PubMed lists PMID 28169285 in The American journal of gastroenterology as Clinical Trial, Phase III, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, with publication-date metadata of 2017-02-07 (day precision). PeptideScanner associated the retained record with the identity slug plecanatide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0`](#source-pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0))

### Paragraph 2

This page reproduces bounded bibliographic metadata attributed to PubMed. Its title and publication details are source metadata, not PeptideScanner's endorsement or an assertion of safety, efficacy, or scientific truth. ([`pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0`](#source-pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0))

## Sources

<a id="source-pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0"></a>
- **A Randomized Phase III Clinical Trial of Plecanatide, a Uroguanylin Analog, in Patients With Chronic Idiopathic Constipation. · retained source version 1:2022-04-08:current:9ef724a102b0ee35a2c3b85c6ae867e595e4f4e5afc273e2aa9bb8d9b9440ef5** — PubMed; class A. [Open source](https://pubmed.ncbi.nlm.nih.gov/28169285/) (`pubmed-observation-pmid-28169285-2022-04-08-9ef724a102b0`)

## Correction lineage

No correction is recorded for this version.

## Reporting boundaries and unknowns

PeptideScanner reproduces bounded bibliographic metadata attributed to PubMed. It does not summarize or endorse the article's findings.

- Sources outside the selected public PeptideScanner bundle may exist and are not represented by this object.
- This object does not determine whether cited records agree, corroborate one another, or establish scientific truth.
- This object does not determine safety, efficacy, causality, or suitability for any person.

Methodology: https://peptidescanner.com/methodology/
Medical disclaimer: https://peptidescanner.com/medical-disclaimer/

## Suggested citation

PeptideScanner. "A Randomized Phase III Clinical Trial of Plecanatide, a Uroguanylin Analog, in Patients With Chronic Idiopathic Constipation." Version 1, published 2026-08-13. https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-28169285-plecanatide-v1.json SHA-256: caf39155b44540101049a94958499ece72c21a41e0d3d036f15514005cf26fa7.