# Linaclotide for the treatment of irritable bowel syndrome with constipation: is it time to reshuffle the deck?

> PubMed lists PMID 23791794 in Gastroenterology as Journal Article, Comment, with publication-date metadata of 2013-06-20 (day precision). PeptideScanner associated the retained record with the identity slug linaclotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

- Evidence object: `story:pubmed-pmid-23791794-linaclotide:v1`
- Evidence domain: Literature metadata
- Date in source: 2018-12-02
- Source checked: 2026-07-30
- Published by PeptideScanner: 2026-08-13
- Story landing page: https://peptidescanner.com/stories/pubmed-pmid-23791794-linaclotide/
- JSON record: https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-23791794-linaclotide-v1.json
- Content SHA-256: `86e8e45835dd88183275e53495ad6cbb53d9c527d7b189d5e2d26582c497b258`

## Claims and source pins

### Headline

Linaclotide for the treatment of irritable bowel syndrome with constipation: is it time to reshuffle the deck? ([`pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d`](#source-pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d))

### Summary

PubMed lists PMID 23791794 in Gastroenterology as Journal Article, Comment, with publication-date metadata of 2013-06-20 (day precision). PeptideScanner associated the retained record with the identity slug linaclotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d`](#source-pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d))

### Paragraph 1

PubMed lists PMID 23791794 in Gastroenterology as Journal Article, Comment, with publication-date metadata of 2013-06-20 (day precision). PeptideScanner associated the retained record with the identity slug linaclotide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings. ([`pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d`](#source-pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d))

### Paragraph 2

This page reproduces bounded bibliographic metadata attributed to PubMed. Its title and publication details are source metadata, not PeptideScanner's endorsement or an assertion of safety, efficacy, or scientific truth. ([`pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d`](#source-pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d))

## Sources

<a id="source-pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d"></a>
- **Linaclotide for the treatment of irritable bowel syndrome with constipation: is it time to reshuffle the deck? · retained source version 1:2018-12-02:current:ccaa6fe8e76d5d84797728a0f5998cef6feab9b5499d632a0345001a3a41112e** — PubMed; class A. [Open source](https://pubmed.ncbi.nlm.nih.gov/23791794/) (`pubmed-observation-pmid-23791794-2018-12-02-ccaa6fe8e76d`)

## Correction lineage

No correction is recorded for this version.

## Reporting boundaries and unknowns

PeptideScanner reproduces bounded bibliographic metadata attributed to PubMed. It does not summarize or endorse the article's findings.

- Sources outside the selected public PeptideScanner bundle may exist and are not represented by this object.
- This object does not determine whether cited records agree, corroborate one another, or establish scientific truth.
- This object does not determine safety, efficacy, causality, or suitability for any person.

Methodology: https://peptidescanner.com/methodology/
Medical disclaimer: https://peptidescanner.com/medical-disclaimer/

## Suggested citation

PeptideScanner. "Linaclotide for the treatment of irritable bowel syndrome with constipation: is it time to reshuffle the deck?" Version 1, published 2026-08-13. https://peptidescanner.com/evidence/v1/objects/pubmed-pmid-23791794-linaclotide-v1.json SHA-256: 86e8e45835dd88183275e53495ad6cbb53d9c527d7b189d5e2d26582c497b258.