{"changeSha256":"b71e402a1dc79d2b9e6adfd239ae6e9ff8fb708dc3d6b25537a9ccb6bf1d408a","changedAt":"2026-09-15","changedFields":[{"after":"FDA compounding assessment in the cited records","before":"FDA compounding safety review; final determination pending","field":"Status"},{"after":"FDA's July 2026 briefing evaluates TB-500-related bulk drug substances for pharmacy compounding. The briefing is an advisory-process assessment, not a final regulatory determination.","before":"FDA's identity record maps TB-500 to a thymosin beta-4 fragment, while FDA's July 2026 briefing addresses its pharmacy-compounding review. Committee recommendations are nonbinding, and FDA's final determination remains pending.","field":"Evidence note"},{"after":"name: fda-tb-500-identity, fda-tb-500-briefing; aliases: fda-tb-500-identity, fda-tb-500-briefing; category: fda-tb-500-briefing; status: fda-tb-500-briefing; summary: fda-tb-500-identity, fda-tb-500-briefing; evidenceNote: fda-tb-500-briefing","before":"name: fda-tb-500-identity, fda-tb-500-briefing; aliases: fda-tb-500-identity, fda-tb-500-briefing; category: fda-tb-500-briefing; status: fda-tb-500-briefing, fda-pcac-peptide-meeting-2026; summary: fda-tb-500-identity, fda-tb-500-briefing; evidenceNote: fda-tb-500-identity, fda-tb-500-briefing, fda-pcac-peptide-meeting-2026","field":"Claim citations"}],"currentVersion":{"canonicalUrl":"https://peptidescanner.com/peptides/tb-500/versions/3/","version":3},"id":"profile:tb-500:v3","interpretationBoundary":"This event describes a PeptideScanner public-version change. It does not by itself establish that the cited source changed, that a scientific conclusion changed, or that source monitoring is continuous.","kind":"corrected","notice":"We narrowed the status wording to what the dated FDA briefing establishes. A briefing prepared for an advisory process does not establish the current absence of a later final decision. Related substance identities remain distinct.","peptideSlugs":["tb-500"],"previousChangeEvent":{"path":"/corrections/v1/profiles/tb-500/v2.json","sha256":"0643b4ce302f6969c30d150f1ec757854581b114c82b3e89015e779d3026bfd3"},"previousVersion":{"canonicalUrl":"https://peptidescanner.com/peptides/tb-500/versions/2/","version":2},"schemaVersion":"peptidescanner-public-correction-lineage-event/v1","sourceRecords":[{"id":"fda-tb-500-briefing","name":"U.S. Food and Drug Administration","sourceClass":"A","title":"FDA briefing document for TB-500","url":"https://www.fda.gov/media/193349/download","verifiedAt":"2026-07-29"}],"subject":{"slug":"tb-500","type":"profile"}}