# ClinicalTrials.gov record history: NCT05726227

- Peptide profile: [semaglutide](https://peptidescanner.com/peptides/semaglutide/)
- Human timeline: https://peptidescanner.com/stories/clinicaltrials-gov-nct05726227-semaglutide/
- JSON object: https://peptidescanner.com/clinical-trials-history/v1/trials/nct05726227.json
- Source observed: 2026-08-23T23:32:33.000Z
- Published by PeptideScanner: 2026-08-23
- Source observation SHA-256: `6ae8058d20bbb511d9250d19ac0bd3475945bb56f0057fdb437648218b72606e`
- Object content SHA-256: `24b81ac9185e572692a908d69174ad5c4fd10feab122e17e3d7304851161214b`

## Reporting boundary

ClinicalTrials.gov lists this public record-history version and identifies its submitted date and the source modules marked as changed. PeptideScanner does not infer what changed inside a module, why it changed, whether the change is material, whether the study is trustworthy, or whether an intervention is safe or effective.

## Public history versions

| Version | Submitted | Last submitted QC | Status | Study type | Source-declared changed modules | Exact source | Record SHA-256 |
| ---: | --- | --- | --- | --- | --- | --- | --- |
| 1 | 2023-02-03 | 2023-02-03 | NOT_YET_RECRUITING | INTERVENTIONAL | None listed | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=1&tab=history) | `b158a7f32b35a61a8d77f365701d6c4fd4dc3cf2068fea60d3aff5e5784897c1` |
| 2 | 2023-02-20 | 2023-02-20 | NOT_YET_RECRUITING | INTERVENTIONAL | Contacts/Locations, Eligibility, Outcome Measures, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=2&tab=history) | `bfc012ab7e72b6ad053e12149184726960c5582b18339c78cc8f77c3ed864d48` |
| 3 | 2023-04-03 | 2023-04-03 | NOT_YET_RECRUITING | INTERVENTIONAL | Contacts/Locations, Outcome Measures, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=3&tab=history) | `d617ab69289173d0ee26699e1361adced3ed2951c8728809d30563bd687eed9c` |
| 4 | 2023-04-27 | 2023-04-27 | NOT_YET_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=4&tab=history) | `61517207611c1cdfcdd9ff0674998049fdbc3fefab9f54ba514417a8d65bf446` |
| 5 | 2023-05-23 | 2023-05-23 | NOT_YET_RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=5&tab=history) | `c8da06098cdc1565662ebbddbefa1c42bebcc1ea216d1591125914c396baf337` |
| 6 | 2023-07-10 | 2023-07-10 | NOT_YET_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=6&tab=history) | `65521e4ce4f8005fc86af78b20f6dc6935c5d4803672ffcf23116be268b51de2` |
| 7 | 2023-07-11 | 2023-07-11 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=7&tab=history) | `f18d7775043b3c8e540984e461b27c09d35ff123272db525640c85fc34919e45` |
| 8 | 2023-07-14 | 2023-07-14 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=8&tab=history) | `3b13f452c2de76fecbf434ca91f8c228344d6ef77a283e7a8751149856b6d704` |
| 9 | 2023-07-20 | 2023-07-20 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=9&tab=history) | `d8114f172d2cb531fb129e154de8d1d3d2c743cb41b40f5fd092db0878c6ac08` |
| 10 | 2023-07-21 | 2023-07-21 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=10&tab=history) | `775607c036ff83b00a38820480af1abd52975d1952d5b7f379818596be9a7185` |
| 11 | 2023-08-10 | 2023-08-10 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=11&tab=history) | `c79052de72009260a2168045f7b710e5621db5b7ab2bf067e8bb58bad705ca65` |
| 12 | 2023-08-15 | 2023-08-15 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=12&tab=history) | `5e6b4a51755942524e16a38e43a90e1d86b37af46c505aec44936d0d7cf27a65` |
| 13 | 2023-08-25 | 2023-08-25 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=13&tab=history) | `fb7855b1b58775f449992f0630823e86e116b5a641c9bbba1f508dff95f23c64` |
| 14 | 2023-08-28 | 2023-08-28 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=14&tab=history) | `3052db0eb8658487be8ac495ceed3fad1f2e30204b44093be134ab0584c27230` |
| 15 | 2023-09-01 | 2023-09-01 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=15&tab=history) | `5d977d91f0b718af13935ed873b33a8c628291ade516b6a1a8050bf384c05925` |
| 16 | 2023-09-14 | 2023-09-14 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=16&tab=history) | `2079f6890ad068bd5520c0e47bc9699801f442debc0cb074214a6a1e525af9f8` |
| 17 | 2023-10-02 | 2023-10-02 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=17&tab=history) | `7ec4f02343262563c67e90f95d6712916496598a314273c25dad3972e1c0e737` |
| 18 | 2023-10-09 | 2023-10-09 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=18&tab=history) | `6adbaeb092f7cedd00de86ebe171d15e477ca61ea736a36f29fb7be95a79750c` |
| 19 | 2023-10-26 | 2023-10-26 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=19&tab=history) | `ebd8dd91fc0726e3ed9c0901a6451f001737845cc8696c3f7111cf5e7734180a` |
| 20 | 2023-11-06 | 2023-11-06 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=20&tab=history) | `be460b4bf754636b46b4743c9a3c23306a5bedbed3ed157296cd69ae9764f10a` |
| 21 | 2023-11-09 | 2023-11-09 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=21&tab=history) | `a7f67d10e8219c4ce2ab2ab6db11d72356dc6fb0ff495f62ba2b9743d2de858e` |
| 22 | 2023-11-22 | 2023-11-22 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=22&tab=history) | `36dfb4c80d9a6b84d72153ddd6dabc64bcf89d7ba8ec3f114fc9e004d3c5e9be` |
| 23 | 2023-11-24 | 2023-11-24 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=23&tab=history) | `48d1a0c98eb8121730a83b2cf8e00b50f57c2e9a141e39cd7a17a99b8ec4d1c1` |
| 24 | 2023-11-27 | 2023-11-27 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=24&tab=history) | `2dd51623d72c1d127fbc84541917ecfeccbcb951ce0e2c10ea59589dd39ec7c4` |
| 25 | 2023-11-30 | 2023-11-30 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=25&tab=history) | `78ce8d442ed8369b093f886943f42cadd50d3ebfcd1712909a241f0936eb586e` |
| 26 | 2023-12-04 | 2023-12-04 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=26&tab=history) | `d313af91d5eb0f1d558ea883f08641addae5f43a264a600d6544b868939bfd7f` |
| 27 | 2023-12-11 | 2023-12-11 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=27&tab=history) | `6ed8536d4842995c146684aa66dfef7354b42e2e3e56d794d381ff7b3efe13a6` |
| 28 | 2024-01-08 | 2024-01-08 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=28&tab=history) | `6177ed84ad0d25e791cf1a0af3ce0da57df6522eccff84a58686721e5d3b27ce` |
| 29 | 2024-01-15 | 2024-01-15 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=29&tab=history) | `ad637deccd01d693753038381d6ad37971008f4326277663bee5221de12fb913` |
| 30 | 2024-01-17 | 2024-01-17 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=30&tab=history) | `6062ee867ad7d1ae80a1b6a54266945cd28c6666b0cb14ebcbbf4e5d146ccf6b` |
| 31 | 2024-01-24 | 2024-01-24 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=31&tab=history) | `2b63b0b59d9386f9de7f3640666cf50ab5b8792276c75afe834049341e5b96de` |
| 32 | 2024-01-26 | 2024-01-26 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=32&tab=history) | `317804068b475dbf93cf9e43f279eec07dbab9d09c51f27326e77bf7081eedf5` |
| 33 | 2024-01-30 | 2024-01-30 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=33&tab=history) | `32a5965f971294ec737b93bec04b45351e2ee49b15a5f15db8d77d43f11d1060` |
| 34 | 2024-02-05 | 2024-02-05 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=34&tab=history) | `a91d0339c2ea5398df8d49645b3d096bd2706b6ec8610a8452c1f8ab90cd3027` |
| 35 | 2024-02-12 | 2024-02-12 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=35&tab=history) | `0b749403e20af49cd728ad0a10159e6a6ad340c2978945d5f4d6e7f69463d7e0` |
| 36 | 2024-02-13 | 2024-02-13 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=36&tab=history) | `f3337c88ed73c2c579df0187c46db6edac207a08a60920f705fffcca7c20571a` |
| 37 | 2024-02-29 | 2024-02-29 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=37&tab=history) | `e531352ef9cafb5581c7c33f980b48ef56d877ec99b0c8e1c45ed475a9e2d728` |
| 38 | 2024-03-04 | 2024-03-04 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=38&tab=history) | `6e9bcbb76df81e9cfd9c618b516a924318763aaadac1d2839bd5e706e59cecce` |
| 39 | 2024-03-11 | 2024-03-11 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=39&tab=history) | `f630eb0c1a061a545f3259a516fbb1d84bebacf49332ad47c07278873845d0fa` |
| 40 | 2024-03-26 | 2024-03-26 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=40&tab=history) | `4449082beff944edae1a1498918985bc0ee04e0921c7c90a7a69accf535fb707` |
| 41 | 2024-05-06 | 2024-05-06 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=41&tab=history) | `d560e65eea2df0b6cf989a0566ab3e6ebf0d832ae2528dbe2a167193e86ff3e9` |
| 42 | 2024-06-04 | 2024-06-04 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=42&tab=history) | `95dea91f85162c047ca5f2f39e90edc8fc45a8545baec84258f767a2dc581a75` |
| 43 | 2024-06-11 | 2024-06-11 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=43&tab=history) | `c6e0c6f7c6d5deaa18d6d1202acff50a33c790b77173d2fe623294d9faa9828c` |
| 44 | 2024-06-19 | 2024-06-19 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=44&tab=history) | `c105d6cc8463c40c7526ff57d5c1fc0203a8678ef6dff81479e777c656eb3d53` |
| 45 | 2024-07-02 | 2024-07-02 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=45&tab=history) | `b46d755cbb1abb0c877d2c3e7fb2002d7a424288279a8bbdaa4715c95398c5da` |
| 46 | 2024-07-05 | 2024-07-05 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=46&tab=history) | `ad004683029375d345d36a6eeac8dcc56d5a2ab4c7921ac0fc4883eaf741c6bc` |
| 47 | 2024-08-05 | 2024-08-05 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=47&tab=history) | `c13f1d9661f52fe42e25bf0e66d9e5f288b2b22cc8a417718b35df33e6668cc1` |
| 48 | 2024-11-15 | 2024-11-15 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=48&tab=history) | `d93ad226a5b319283b99bd6f014145cdcbd3128cdbb0feafae3081451659dca5` |
| 49 | 2024-11-16 | 2024-11-16 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=49&tab=history) | `c41e2007b21367330c781a241e88757e20adf350b393325328d5cc88e7872568` |
| 50 | 2025-01-28 | 2025-01-28 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=50&tab=history) | `7f71f1981669daca29a9e5b8eae6cc2727be3a1d75a9f79c6e37a175436505d0` |
| 51 | 2025-09-18 | 2025-09-18 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=51&tab=history) | `5d164431f79b9764915a6a4fcdf71449aa2146d0630b0d8bffa3cb3576e4e307` |
| 52 | 2025-11-21 | 2025-11-21 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=52&tab=history) | `62041321ac62e38a566495fb793f7ee81538e250ccff742603b22a40d2cf52e2` |
| 53 | 2026-04-20 | 2026-04-20 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=53&tab=history) | `38fb4de04ef240c2060d6a4ef7205e7675857fbff44f25789c549e2d86978ede` |
| 54 | 2026-06-15 | 2026-06-15 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=54&tab=history) | `54b9f21c51927cb3b5352aa4482ca13a3d3d3c99e5869e253e53a3e5ef50e309` |
| 55 | 2026-08-06 | 2026-08-06 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT05726227?a=55&tab=history) | `46d6fca30c5d81f5ac1b4167657c1e0bcad2a68a44a8ff5527472d9b2061df66` |