# ClinicalTrials.gov record history: NCT04216589

- Peptide profile: [semaglutide](https://peptidescanner.com/peptides/semaglutide/)
- Human timeline: https://peptidescanner.com/stories/clinicaltrials-gov-nct04216589-semaglutide/
- JSON object: https://peptidescanner.com/clinical-trials-history/v1/trials/nct04216589.json
- Source observed: 2026-08-23T23:32:33.000Z
- Published by PeptideScanner: 2026-08-23
- Source observation SHA-256: `6ae8058d20bbb511d9250d19ac0bd3475945bb56f0057fdb437648218b72606e`
- Object content SHA-256: `0f28b6b2a70881195c02eb7a8a0492e5fca9916258d3266380eb09afb6bae00f`

## Reporting boundary

ClinicalTrials.gov lists this public record-history version and identifies its submitted date and the source modules marked as changed. PeptideScanner does not infer what changed inside a module, why it changed, whether the change is material, whether the study is trustworthy, or whether an intervention is safe or effective.

## Public history versions

| Version | Submitted | Last submitted QC | Status | Study type | Source-declared changed modules | Exact source | Record SHA-256 |
| ---: | --- | --- | --- | --- | --- | --- | --- |
| 1 | 2019-12-30 | 2019-12-30 | NOT_YET_RECRUITING | INTERVENTIONAL | None listed | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=1&tab=history) | `12f7c7e6d51ed3756068a7637881edd414d37d5022e686a9084b9bca11bca1f5` |
| 2 | 2020-07-01 | 2020-07-01 | NOT_YET_RECRUITING | INTERVENTIONAL | Eligibility, Outcome Measures, Study Description, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=2&tab=history) | `066715c58656484a261c099aab50e5927a8040a93ca658249aeb05f2ef6d8b0f` |
| 3 | 2020-07-06 | 2020-07-06 | NOT_YET_RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=3&tab=history) | `1aaaf998d2f5871c4c27029b8a3c7cde4eec0960a94106b0b442691ece98791e` |
| 4 | 2020-08-04 | 2020-08-04 | NOT_YET_RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=4&tab=history) | `1df357478dbc2a5ff1fba464aba03b5790b02540f47dafafa3c271fa67cfa307` |
| 5 | 2020-08-17 | 2020-08-17 | NOT_YET_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=5&tab=history) | `ac90db15a5b86cf3d074dbc8cfd02ae4ceec0bf965b04d567f0680a618c39159` |
| 6 | 2020-09-21 | 2020-09-21 | NOT_YET_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=6&tab=history) | `59a4fa135e1d11fd67a2d4ebd93614a66ddcc8a7ab7ab71575298d2b56d0076c` |
| 7 | 2020-09-25 | 2020-09-25 | NOT_YET_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=7&tab=history) | `31ebaa4591bd1741c0645545bdfbad16278a1311eb0509b8a567d5c706a52295` |
| 8 | 2020-10-06 | 2020-10-06 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=8&tab=history) | `5564679b4518b2c5de3016244f4adc076a4c6cdcff7917e7fab722bb4650653e` |
| 9 | 2020-10-12 | 2020-10-12 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=9&tab=history) | `8a0daf4013bcfda1257fd378c0b54381ac7da81f9f3a9d7e8689d8b43deb14a5` |
| 10 | 2021-04-08 | 2021-04-08 | RECRUITING | INTERVENTIONAL | IPDSharing, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=10&tab=history) | `cb829135317db03689c3a4eaeb00ff985d7b03f8fde1113690354419aad020e8` |
| 11 | 2021-04-20 | 2021-04-20 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=11&tab=history) | `f51dff49165d5fc1bda5eb7ba6047000666e256cc22be08abfc56cf147b648cd` |
| 12 | 2021-05-13 | 2021-05-13 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=12&tab=history) | `7b94b4c16bb7e4a974068d312d66c7981e8e9c01b15d8116130420a7fb289650` |
| 13 | 2021-06-18 | 2021-06-18 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=13&tab=history) | `43e2dfe29a6a0a112560dd3637e02e3dd4bb64c556b62ea1d60e22fc984e504c` |
| 14 | 2021-06-21 | 2021-06-21 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=14&tab=history) | `a135806edcb81d57dda9715f10760e3c2c4f0c67694a9bb63578e7c1b0491cc7` |
| 15 | 2021-07-07 | 2021-07-07 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=15&tab=history) | `159d829ca738d8a4c278f17806002479df2b17236c567de0aa0bacdccb1018a7` |
| 16 | 2021-07-30 | 2021-07-30 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=16&tab=history) | `b9e0daa4a7c325a00ea397c4a9eaec0ef12fc4a407aed526b168953f00b3de9a` |
| 17 | 2021-08-20 | 2021-08-20 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=17&tab=history) | `5a44cccbb93a012120765d94cb00a22268ceb8b48e7bec59ef906c25b104c0b3` |
| 18 | 2021-09-03 | 2021-09-03 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=18&tab=history) | `0c2615c903f95cfcafcf204b2fa0936c60feb3210ae0d538cc81ea45e63b3154` |
| 19 | 2021-10-27 | 2021-10-27 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=19&tab=history) | `77e2bf6c625753330c50f03f060de655c6e10d213cd2abf00db1878c4d83d43e` |
| 20 | 2021-11-15 | 2021-11-15 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=20&tab=history) | `e4bda57090614b56ea8686d7921ec6eb4632c4ea8fff3b12033c1245a1d6b375` |
| 21 | 2022-01-28 | 2022-01-28 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=21&tab=history) | `34b87e7b3041fe496240b6238bb51d8af55507d986411c969c02cf0cd103629c` |
| 22 | 2022-06-20 | 2022-06-20 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=22&tab=history) | `0fb19becdcc3fb7320cecc320719c3489434f86bb106043c60f81cab7d347f79` |
| 23 | 2022-10-06 | 2022-10-06 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Design, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=23&tab=history) | `b463f45837a87c4323d7934c96e6aa531524c927927d26e20be006a187e30720` |
| 24 | 2022-12-13 | 2022-12-13 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=24&tab=history) | `8329c69fb1c751a78d1fc163811546ca6d6b1ecf115443ef24f87c9ed6a468d8` |
| 25 | 2023-04-12 | 2023-04-12 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=25&tab=history) | `ff0721eaf6d2a3d4dffbfa724875e56dce4323b1a952da71d1346cb26cc75605` |
| 26 | 2023-09-19 | 2023-09-19 | COMPLETED | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=26&tab=history) | `44556363fc96cc7cc3805acc87e1c78ac574e0106e5d7a794f09d181c9687384` |
| 28 | 2024-04-22 | 2024-04-22 | COMPLETED | INTERVENTIONAL | Baseline Characteristics, Outcome Measures, Outcome Measures (Results), Participant Flow, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=28&tab=history) | `6a1322de0928f48c8f82485d85838039e206fffca4f550f3045f3f295893bdd7` |
| 29 | 2024-09-06 | 2024-09-06 | COMPLETED | INTERVENTIONAL | Outcome Measures, Outcome Measures (Results), Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT04216589?a=29&tab=history) | `0bd2bf7f1cd6ed4a3ba5554f8b04d5756c1269cbda72c2738afbc335228990f9` |