# ClinicalTrials.gov record history: NCT00225420

- Peptide profile: [leuprolide](https://peptidescanner.com/peptides/leuprolide/)
- Human timeline: https://peptidescanner.com/stories/clinicaltrials-gov-nct00225420-leuprolide/
- JSON object: https://peptidescanner.com/clinical-trials-history/v1/trials/nct00225420.json
- Source observed: 2026-08-23T23:32:33.000Z
- Published by PeptideScanner: 2026-08-23
- Source observation SHA-256: `6ae8058d20bbb511d9250d19ac0bd3475945bb56f0057fdb437648218b72606e`
- Object content SHA-256: `b7de5b8d0b4d10e7757b8790a5ce5577b3ff3e41f6a369bcd21473f9f5a08ea0`

## Reporting boundary

ClinicalTrials.gov lists this public record-history version and identifies its submitted date and the source modules marked as changed. PeptideScanner does not infer what changed inside a module, why it changed, whether the change is material, whether the study is trustworthy, or whether an intervention is safe or effective.

## Public history versions

| Version | Submitted | Last submitted QC | Status | Study type | Source-declared changed modules | Exact source | Record SHA-256 |
| ---: | --- | --- | --- | --- | --- | --- | --- |
| 1 | 2005-09-21 | 2005-09-21 | RECRUITING | INTERVENTIONAL | None listed | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=1&tab=history) | `e95f034b169e999cf7dd1cd2bfd0fcf59a7cf37099177ca188c5fa4020b568cb` |
| 2 | 2005-09-26 | 2005-09-26 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Design, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=2&tab=history) | `01d960a85286c802299d5b06fea29b2cb3d3d8fc423221522863ba080c6eb088` |
| 3 | 2006-06-09 | 2006-06-09 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=3&tab=history) | `52aba55f714a9001bc47eb65f5ed3e8d4c29fbf726fc8cb7a7778dea339dead5` |
| 4 | 2007-05-23 | 2007-05-23 | RECRUITING | INTERVENTIONAL | Study Design, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=4&tab=history) | `ea7a0780c6f19b1e6763594e062efb37a16313ac2f61d65773b47659056a98f9` |
| 5 | 2007-06-13 | 2007-06-13 | RECRUITING | INTERVENTIONAL | Arms and Interventions, Conditions, Contacts/Locations, Eligibility, Outcome Measures, Sponsor/Collaborators, Study Description, Study Design, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=5&tab=history) | `be3cfae96421ebe9263cf15544d9eb3fa4f0346bce6436b7e0a9614813bb8431` |
| 6 | 2007-09-25 | 2007-09-25 | RECRUITING | INTERVENTIONAL | Study Description, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=6&tab=history) | `c01635f3218b99a23bdb4cc5f148b6b0e2529d1634e2e55aabd0e77a959e78a3` |
| 7 | 2007-10-25 | 2007-10-25 | RECRUITING | INTERVENTIONAL | Arms and Interventions, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=7&tab=history) | `c2993e6b980dedc213010e2b9f4a1796b2086dfd16a5a62d8cf6ed7f7884bec1` |
| 8 | 2007-12-25 | 2007-12-25 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=8&tab=history) | `cd231924dad06be5764a3c1ac9825d7ec63645199c64e98485b78367d1b2276c` |
| 9 | 2008-03-22 | 2008-03-22 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=9&tab=history) | `9e1d6d980b43730c31a2c6c06423c9bd8f8f27ea33efc2e86f77b7a5950ae9ea` |
| 10 | 2008-05-23 | 2008-05-23 | RECRUITING | INTERVENTIONAL | Arms and Interventions, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=10&tab=history) | `3ab989b59d6e3120c1f0ff529e525d1bbdc3ed455f58febf00d0c7bb31a06bc0` |
| 11 | 2008-06-07 | 2008-06-07 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=11&tab=history) | `c2a8f1fb578da1fe341b0ee0c88a8da5eb3e5a505009f289bfa765dd6a2fcd20` |
| 12 | 2008-07-23 | 2008-07-23 | RECRUITING | INTERVENTIONAL | Study Design, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=12&tab=history) | `2daf1921c6df9060a6d04f2d39089b3fbb89d48ffca5503824b1feee4785d1d7` |
| 13 | 2008-07-29 | 2008-07-29 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=13&tab=history) | `0db5e5426ff74cd4f0f721da99e44e00d6a59ec52a18de2f0c75cce50e898540` |
| 14 | 2008-10-22 | 2008-10-22 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=14&tab=history) | `5fe88df41d252d58de805e982389ffa505faeaf38f2d0c833fc8f4382e7ad3bf` |
| 15 | 2008-11-25 | 2008-11-25 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=15&tab=history) | `2c8b123cd30a0a7a298d6d72eb6234e911e19f08d3da10a1f05716c44057caaa` |
| 16 | 2009-02-06 | 2009-02-06 | RECRUITING | INTERVENTIONAL | Arms and Interventions, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=16&tab=history) | `5450f76a3f313f3d2524ad6ecbc3c6f1c3f67efee6962134e416f72928e435df` |
| 17 | 2010-11-09 | 2010-11-09 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=17&tab=history) | `7c3cbbf40f78245951df2577f39aa70d4b575ac1afa827f9a455bb7fc17524fe` |
| 18 | 2011-05-31 | 2011-05-31 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Arms and Interventions, Outcome Measures, Oversight, Sponsor/Collaborators, Study Design, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=18&tab=history) | `fa8a5ba7a962e8f2db7b86687560b4f2f11a5ed6d5657a7e2f6d62fd8c825e1c` |
| 19 | 2012-03-05 | 2012-03-05 | ACTIVE_NOT_RECRUITING | INTERVENTIONAL | Sponsor/Collaborators, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=19&tab=history) | `f1d01b23e3d248cd86dd908c4cd363d0f947c2d3a9d6f70e8d30b3065e0e5b01` |
| 20 | 2012-09-10 | 2012-09-10 | COMPLETED | INTERVENTIONAL | Arms and Interventions, Study Design, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=20&tab=history) | `03b2303e2ad5c7d40ee0f362e89c6c95b4b1aa0af4090163b38e1277cc38da86` |
| 21 | 2012-09-18 | 2012-09-18 | COMPLETED | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=21&tab=history) | `0a1af487bfed656972dd9bd0e01dfebd825db84619d96b160697489033c0872a` |
| 22 | 2016-01-20 | 2016-01-20 | COMPLETED | INTERVENTIONAL | Eligibility, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=22&tab=history) | `cf87695ae925922186befb7edcada7f844b1dd882a1a408c9f3795fc7a908c36` |
| 23 | 2017-04-26 | 2017-04-26 | COMPLETED | INTERVENTIONAL | Adverse Events, Arms and Interventions, Baseline Characteristics, Eligibility, More Information, Outcome Measures, Outcome Measures (Results), Participant Flow, References, Sponsor/Collaborators, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00225420?a=23&tab=history) | `05753a0c376121292f53be6e27e2b9f258249e7254c6ea0ebb9630da9ac17909` |