# ClinicalTrials.gov record history: NCT00223665

- Peptide profile: [leuprolide](https://peptidescanner.com/peptides/leuprolide/)
- Human timeline: https://peptidescanner.com/stories/clinicaltrials-gov-nct00223665-leuprolide/
- JSON object: https://peptidescanner.com/clinical-trials-history/v1/trials/nct00223665.json
- Source observed: 2026-08-23T23:32:33.000Z
- Published by PeptideScanner: 2026-08-23
- Source observation SHA-256: `6ae8058d20bbb511d9250d19ac0bd3475945bb56f0057fdb437648218b72606e`
- Object content SHA-256: `fe08bdc47e6b69c4b9b2344d52847a77b34e277c7f199bf204bff16c657e7b4f`

## Reporting boundary

ClinicalTrials.gov lists this public record-history version and identifies its submitted date and the source modules marked as changed. PeptideScanner does not infer what changed inside a module, why it changed, whether the change is material, whether the study is trustworthy, or whether an intervention is safe or effective.

## Public history versions

| Version | Submitted | Last submitted QC | Status | Study type | Source-declared changed modules | Exact source | Record SHA-256 |
| ---: | --- | --- | --- | --- | --- | --- | --- |
| 1 | 2005-09-16 | 2005-09-16 | RECRUITING | INTERVENTIONAL | None listed | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=1&tab=history) | `77d96398d31b994196f6e84eabd25d0a02cf84549651ea082b5567678595db6a` |
| 2 | 2006-01-26 | 2006-01-26 | RECRUITING | INTERVENTIONAL | Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=2&tab=history) | `8efe891bf34c391a2cd1ae9cdf560e666fa10428835a837030bddd0ec21d6f77` |
| 3 | 2006-08-25 | 2006-08-25 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=3&tab=history) | `b26e82e74ef4d3c5a615f9e1d67ce275c4d2a8bef30d3e59c451caca6ded8a59` |
| 4 | 2007-02-23 | 2007-02-23 | RECRUITING | INTERVENTIONAL | Oversight, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=4&tab=history) | `eaab6ec14513084aac56b4c0424dfe446cf7fd5886d3a4bb631155f504c96faa` |
| 5 | 2007-09-11 | 2007-09-11 | RECRUITING | INTERVENTIONAL | Arms and Interventions, Outcome Measures, Study Design, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=5&tab=history) | `16f07d9e26982dd4f6edb571c76cae2ca97c6c27937f6e58ccf09e8d3de8e0cb` |
| 6 | 2007-11-26 | 2007-11-26 | RECRUITING | INTERVENTIONAL | Arms and Interventions, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=6&tab=history) | `6bede18997167b41e0aff3b6acc7ce4f3f4b8e9cf3eaad4425377b149d47cbf1` |
| 7 | 2008-03-06 | 2008-03-06 | RECRUITING | INTERVENTIONAL | Sponsor/Collaborators, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=7&tab=history) | `28a332fdd95fbc0ed421e54e00b548ad1b3b6ba9534e8cf6c4f2f01e02207b9b` |
| 8 | 2008-10-10 | 2008-10-10 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=8&tab=history) | `42a93cbe54bdbeb7a105909327d81c00ec4cec41d4cbee46357dc38e2082db07` |
| 9 | 2009-05-11 | 2009-05-11 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=9&tab=history) | `09ecf28fb9cadd91ee6f263b3bcef596fa386df5fba6e6d2cf9bf26ab8d66fbe` |
| 10 | 2009-12-30 | 2009-12-30 | RECRUITING | INTERVENTIONAL | Contacts/Locations, Outcome Measures, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=10&tab=history) | `83119da4e87e4b666eebd4c59d3d6b38204b4310284f32059c1378d2f51b2d5a` |
| 11 | 2010-06-25 | 2010-06-25 | RECRUITING | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=11&tab=history) | `7b10fc293e3735fceb93509299ff4987291524dc20f79fe37379122558b019dc` |
| 13 | 2018-04-10 | 2018-04-10 | COMPLETED | INTERVENTIONAL | Adverse Events, Arms and Interventions, Baseline Characteristics, Conditions, Contacts/Locations, Eligibility, IPDSharing, More Information, Outcome Measures, Outcome Measures (Results), Oversight, Participant Flow, Sponsor/Collaborators, Study Description, Study Design, Study Identification, Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=13&tab=history) | `9abfafb63f9e8de06dd86721e39b7e90b88b593f5b91ca345eab2b6b02eeacc7` |
| 14 | 2018-08-03 | 2018-08-03 | COMPLETED | INTERVENTIONAL | Study Status | [ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT00223665?a=14&tab=history) | `38e8f515bf3594c0eb5e1a6d16d1425abea982d869ec3691cfa4bc6e9d2c2a13` |